Part 1:
Jiaogulan increases equine circulation
Jiaogulan, scientifically known as Gynostemma pentaphyllum, has a long history of traditional use and is widely recognized for its health-promoting properties. It is commonly used as a dietary supplement for horses, where it is valued for its ability to support circulation (Kellon, 2006). This herb contains two primary classes of active compounds that contribute to its beneficial effects. The first group consists of gypenosides, which are dammarane-type saponins. These compounds are largely responsible for many of jiaogulan’s adaptogenic and cardiovascular benefits (Kellon, 2006). The second group includes flavones, which are plant-based water-soluble pigments (Geleijnse 2008). Research has shown that gypenosides stimulate the release of endothelium-derived nitric oxide (Tanner et al., 1999), a signaling molecule that plays a critical role in vascular function. Nitric oxide acts as a powerful vasodilator, meaning it relaxes the smooth muscles of blood vessels, allowing them to widen. This dilation improves blood flow throughout the body, particularly to the extremities, which can enhance nutrient delivery, oxygen transport, and overall circulatory efficiency (Kellon, 2006). These combined effects make jiaogulan a unique botanical with significant potential for supporting cardiovascular health and systemic resilience.
References:
Geleijnse, Johanna M., and Peter CH Hollman. "Flavonoids and cardiovascular health: which compounds, what mechanisms? 1." The American journal of clinical nutrition 88.1 (2008): 12-13.
Kellon, Eleanor M., and Equine Nutritional Solutions. "Use of the Herb Gynostemma Pentaphyllum and the Blue-green Algae Spirulina Platensis in Horses." Proceedings of the 3rd European Equine Nutrition & Health Congress. 2006.
Tanner, Miles A., et al. "The direct release of nitric oxide by gypenosides derived from the herb Gynostemma pentaphyllum." Nitric oxide 3.5 (1999): 359-365.